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Prove-it™ Sepsis

Prove-it™ Sepsis TubeArray

Accurate DNA-based identification of 60 bacterial pathogens and antibiotic resistance markers in a single assay!

Prove-it™ Sepsis assay identifies sepsis-causing bacteria and fungi from positive blood culture in only 3,5 hours. Thus, it provides essential information for the treatment of septic patients 1 - 3 days earlier than traditional methods.

  • Method: the highly reliable DNA-based identification is carried out by broad-range PCR followed by specific identification on a microarray.
  • Coverage: 60 bacteria and mecA methicillin resistance marker in one assay. View the complete pathogen panel here. Please note that targets marked with an asterix (*) are available only on the Prove-it™ Sepsis StripArray assay.
  • Performance: Prove-it™ Sepsis results correlate extremely well with the results of traditional sub-culturing based Gold standard methods. The clinical performance has been evaluated by analyzing more than 3,300 patient samples with excellent results: 95 % sensitivity and 99 % specificity. *The Lancet 2010
  • Results: Semi-automated assay detection and analysis with Prove-it™ Advisor software on the Prove-it™ TubeArray System or the Prove-it™ StripArray System. The results are presented in a clear and informative manner.
  • Prove-it™ Sepsis assay is also available on StripArray with a larger content.

Get started with Prove-it™ Sepsis!

*Tissari P, Zumla A, Tarkka E, Mero S, Savolainen L, Vaara M, Aittakorpi A, Laakso S, Lindfors M, Piiparinen H, Mäki M, Carder C, Huggett J, Gant V; Accurate and rapid identification of bacterial species from positive blood cultures with a DNA-based microarray platform: an observational study; The Lancet 2010, 9719: vol 375.

 

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